Three Closely Linked Genetic Systems Relevant to Transplantation
نویسندگان
چکیده
منابع مشابه
Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16.
The genetic locus for autosomal dominant adult polycystic kidney disease was recently assigned to chromosome 16 by the finding of genetic linkage to the alpha globin gene cluster. Further study showed that the phosphoglycolate phosphatase locus is also closely linked to both the locus for adult polycystic kidney disease and the alpha globin gene cluster. These findings have important implicatio...
متن کاملGenotyping common SNP and a microsatellite sequence closely linked to waxy gene in rice by DNA based markers
The potential of different DNA based molecular markers was examined for the detection of single nucleotide polymorphism (SNP) in the waxy gene and a microsatellite (SSR) sequence closely linked to it in a collection of rice varieties. DNA was extracted from leaf samples of 68 different rice cultivars by the CTAB method and specific primers were designed for the amplification of waxy gene and SS...
متن کاملReply to "breakpoints and drug exposure are inevitably closely linked".
We thank Alffenaar and colleagues on their very insightful comments regarding the new breakpoints for multidrugresistant tuberculosis (MDR TB) (1). We agree that the impact of the definition goes beyond statistical increases in the prevalence of MDR TB and has a direct impact on who should be treated with first-line regimens. Revision of breakpoints implies changing the regimens on which patien...
متن کاملDetection of closely linked multiple quantitative trait loci using a genetic algorithm.
The existence of a quantitative trait locus (QTL) is usually tested using the likelihood of the quantitative trait on the basis of phenotypic character data plus the recombination fraction between QTL and flanking markers. When doing this, the likelihood is calculated for all possible locations on the linkage map. When multiple QTL are suspected close by, it is impractical to calculate the like...
متن کاملAnti-T-cell reagents for human bone marrow transplantation: ricin linked to three monoclonal antibodies.
Three new reagents that react against human T cells were synthesized by covalently linking the toxin ricin to monoclonal antibodies recognizing differentiation antigens on the surface of T lymphocytes. Each of these immunotoxins selectively inhibited T-cell proliferation when the cells were incubated in the presence of lactose. Multipotent human stem cells were inhibited only at much higher con...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1971
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.68.12.3031